PC system requirements
| Minimum | Recommended | |
| CPU | Intel Core i series | |
| RAM | 8GB | 16GB |
| GPU/Graphics Card | Intel HD Graphics 515 (Gen9) | AMD RX 5500 or comparable |
| Hard Disk | 100GB | 500GB+ SSD |
| OS | Windows 7 64-bit | Windows 10 64-bit |
Mac users (PC version of Invivo)
| OS | Hardware | |
| Not compatible | Apple OS, Parallels | MacBook Air, Mac Mini |
| Fully compatible | Apple Bootcamp (requires a full Windows license) | iMac, MacBook Pro (15in), Mac Pro |
Graphics Card/GPU details
| Brand | Model/Series | Minimum | High-end |
| Intel | HD Graphics Iris Graphics Iris Pro Graphics |
HD Graphics 515-530 | HD Graphics P530 Iris Graphics 540-550 Iris Pro Graphics 580,P555, P580 |
| AMD | RX 5000 Series | RX 5000-5600 | RX 5700-5700 XT |
| Nvidia | 16 Series | GTX 1650, 1660 | GTX 1660 Ti |
Mac users (MAC native version of Invivo)
| Hardware or Software | Minimum requirement |
| Operating system | Apple OS X 10.11 El Capitan |
| CPU | Intel Core i5 2400 or equivalent |
| GPU | Intel Iris Plus Graphics 640 |
| RAM | 4 GB DDR3 |
| HDD Space | 100 GB available |